aciclovir
J - Antiinfectives For Systemic Use -> J05 - Antivirals For Systemic Use -> J05A - Direct Acting Antivirals -> J05AB - Nucleosides And Nucleotides Excl. Reverse Transcriptase Inhibitors -> J05AB01 - Aciclovir
Administration category:
Free
Medicine group:
antiviral
Brand name:
Zovirax
Safety margins
| Weight | ROA | Dosage |
|---|---|---|
|
ROA: iv |
Dosage: min. 5mg/kg 3 dd to max. 15mg/kg 3 dd |
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 30 - 50 |
Interval: 12 Hours |
|||
|
GFR: 10 - 30 |
Interval: 24 Hours |
|||
|
GFR: <10 |
Dosage: overleg met deskundige;alleen orale toediening beschreven |
|||
Renal elimination:
60-90%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: iv: 50% van de normale dosis elke 24 uur, op geleide van de spiegel
Hemo dialysis: iv: 50% van de normale dosis elke 24 uur op geleide van de spiegel, op dialysedagen toedienen na de dialyse
CAV / VVHD: iv: pas voorzichtigheidshalve de dosering aan: normale dosis elke 24 uur, op geleide van de spiegel
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1844.3
Updated: 01/13/2022 - 09:19
Status: Published
General comments
eGFR 10-30: doseer op geleide van bloedspiegels.
CVVH: bij immuungecompromitteerde patient: 1dd 10 mg/kg i.v., onder controle van bloedspiegels.