piperacilline/tazobactam
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01C - Beta-Lactam Antibacterials, Penicillins -> J01CR - Combinations Of Penicillins, Incl. Beta-Lactamase Inhibitors -> J01CR05 - Piperacillin And Enzyme Inhibitor
Administration category:
Free
Medicine group:
antibacterial
File parts:
piperacilline
tazobactam
Brand name:
Tazocin
Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
|
ROA: iv |
Dosage: min. 4000/500mg 3 dd to max. 4000/500mg 4 dd |
||
|
ROA: iv |
Dosage: to max. 16000/2000mg continuous per 24 hours |
||
|
Comments:
bij continue infusie 4000/500 mg loading dose |
|||
Dosage for "I" sensitivity
| Weight | ROA | Load | Dosage | |
|---|---|---|---|---|
|
ROA: iv |
Load: - |
Dosage: 4000/500mg 4 dd |
||
|
Comments:
bij "I" resistentie toedienen met verlengde infusie (3h) |
||||
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 30 - 50 |
Dosage: 4000/500 |
Interval: 8 Hours |
||
|
GFR: 10 - 30 |
Dosage: 4000/500 |
Interval: 12 Hours |
||
Renal elimination:
piperacilline ? %, tazobactam 80%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: iv 4000/500 mg pip-tazo elke 12 uur
Hemo dialysis: iv 4000/500 mg pip-tazo elke 12 uur, na elke dialyseperiode een extra dosis van 2000/250 mg pip-tazo
CAV / VVHD: aanpassing van de dosering is niet noodzakelijk
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1696.6
Updated: 03/21/2024 - 16:53
Status: Published
General comments
CVVH: maximaal 4,5 gram 3dd geven.